I just installed PTO on my Vista x64 machine and I'm having issues with PTO not being able to connect to the Access databases. I'm launching the app as administrator btw.
The actual error code is
Unable to connect to the PTOREG database
160 - SQLSTATE = IM003
Specified driver could not be loaded due to system error 126
(Microsoft Access Driver (.mdb))
I suspect it has to do with the x64 ODBC drivers as under the control panel ODBC system databases the PTO databases aren't there and neither is the Postgres ODBC driver but if you launch the control panel from the WOW64 directory, all three are there just like they are in other OS's. I suspect this might be some sort of known issue but I was unable to find it via searching the forums.