Then you can use custom reports to see how you're doing in hands against these players. You will need to define a little bit more what you mean by "against" though - do you want hands where any one of these players sees the flop? Raises preflop? Makes it to showdown?
For showdown pots you'd add a filter to the blue Filters section in the Reports tab that looks like this:
holdem_hand_player_statistics.id_hand in (SELECT hhps.id_hand from holdem_hand_player_statistics hhps, player p where p.id_player = hhps.id_player and hhps.flg_showdown and p.val_icon = X)
Replace the X with a number between 0 and 15 - each picks out a different group.
I have never found a set of autorate rules that I liked better than the original defaults, but I admit I haven't done a whole lot of research into it.